Hi
PSMD swelling is known to occur in many solvents, but the degree of
swelling strongly varies. A useful reference is this paper from J. Ng
Lee, C. Park, and G. M. Whitesides.

http://pubs.acs.org/cgi-bin/abstract.cgi/ancham/2003/75/i23/abs/ac0346712.html

direct link to the full text here:

http://pubs.acs.org/cgi-bin/article.cgi/ancham/2003/75/i23/pdf/ac0346712.pdf

as you might see the swelling ratio for both Ethyl Alcohol and Acetone
is pretty low, which means that you may flow them for a long time
without any significant alteration to the flow chamber or solvent
contamination with PDMS.

Ciro Chiappini
Ph.D. Student
University of Texas at Austin - Bioengineering Dept.
Dr. Mauro Ferrari Nanomedicine Group



On Sun, 17 Jun 2007 18:18:50 +0800
 "King Lai"  wrote:
> Hi all,
>
> I am planning to make micro channels and chambers by PDMS, but
> acetone/alcohol will flow inside the micro channels. I would like to
>know if
> acetone and alcohol attack PDMS channel. Did anybody has experience
>in using
> acetone in PDMS channel?