Hi all, I'm trying to create shallow microfluidic channels that are covered by a thin, elastomeric membrane (both channel and membrane are only several microns high). I initially tried using the usual PDMS formulations to make the membrane, but they are so flimsy that they immediately collapse into the channel. I increased the cross-linking of the PDMS (see Schmid and Michel, *Macromolecules* 2000, 33, 3042), but the membrane still wasn't stiff enough, and it was too brittle. Ideally, I'd like a material with the following properties -silicone material -heat curable -young's modulus >= 100 MPa -not too brittle The closest candidate that I can find is Dow-Corning's WL-5150 photopatternable PDMS. If anyone has used this compound, do you think I could spin-coat a thin film of it onto a silanized silicon wafer and be able to peel it off after curing, or is this material also too brittle? Is there another compound out there that might do the trick? Thanks in advance, Joshua Tice Graduate Research Assistant Kenis Research Group Dept. of Chemical & Biomolecular Engineering University of Illinois, Urbana-Champaign Roger Adams Laboratory, Room 216A, Box C3 600 South Mathews Avenue Urbana, IL 61801 217-333-2442 (office) 217-244-8068 (fax)