Hi, everyone: I'm currently working on some PDMS microfluidic strcuture and thinking about use a thin polystyrene(PS) layer on top of the PDMS to take advantage of PS surface for bio-application. Has any one done this kinda process before? Is there any specific thing I need to pay attention to? I have not started doing this yet. my concerns are the possible poor bonding between PDMS and polystyrene, and also the possible solvent (I plan to use toluene) diffusion into the PDMS matrix? thanks in advance for your input. Guocheng Shao