Mikael, You can't remove the HMDS as it is not a layer coated on a substrate, but rather substrate areas that have reacted with HMDS to create a non continuous 'monolayer'. You can try to plasma treat the sample to get it hydrophilic. shay -----Original Message----- From: mems-talk-bounces+shay=mizur.com@memsnet.org [mailto:mems-talk-bounces+shay=mizur.com@memsnet.org] On Behalf Of Mikael Evander Sent: Thursday, October 21, 2010 1:29 AM To: 'General MEMS discussion' Subject: [mems-talk] removal of HMDS without affecting the photoresist I'm currently working on a microfluidic project using microelectrodes patterned on glass slides. To test an idea I have, I've patterned the glass wafers with standard positive photoresist and without thinking much about it I used our normal routine which involves priming the glass wafer with HMDS before coating the wafer with resist. Normally that's not a problem as I remove the resist and clean the glass wafers in NaOH to make them hydrophilic again. This time I would like to keep the photoresist intact but still be able to remove the HDMS and make the glass hydrophilic. Would you think that's possible or should I simply try to do this with polyimide or SU8 instead that can withstand solvents a bit better? The reason for using standard photoresist was to make a simple test without going into using new materials/instruments etc . might have been a bad idea :S Thanks! /Mikael