Hi Tsoll, the only reasonable way I know of making such sloped channels is by mechanical micromachining the master, e.g. in PMMA. Precision machining nowadays can make you extremely precise structures (lateral and vertical geometry +-1 µm), it usually takes a quite expensive bit of machinery to do so (e.g. Kern, Precitech, Kugler) but the results are quite amazing. We regularly use precision machining for mold inserts for injection molding of microfluidic channels. The critical bit might be surface roughness, which is higher compared to lithographically defined channels but there are ways of mechanical or chemical polish. With best regards Holger -- Dr. Holger Becker microfluidic ChipShop GmbH Carl-Zeiss-Promenade 10 D-07745 Jena Germany Tel. .+49 (0) 36 41 347 05 80 Fax: +49 (0) 36 41 347 05 90 Geschäftsführerin: Dr. Claudia Gärtner Sitz der Gesellschaft: D-07745 Jena, Germany Amtsgericht Jena: HRB 209251 USt.-IdNr.: DE 221812444 -----Ursprüngliche Nachricht----- Von: mems-talk-bounces+hb=microfluidic-chipshop.com@memsnet.org [mailto:mems-talk-bounces+hb=microfluidic-chipshop.com@memsnet.org] Im Auftrag von Tsoll Doiiu Gesendet: Montag, 28. Februar 2011 03:44 An: mems-talk@memsnet.org Betreff: [mems-talk] Sloped microchannel Hello MEMS community! Does anybody have an idea how to prepare a sloped microchannel in PDMS? Initially I've tried to do like this: spin-coat PR on Si wafer, than hold the wafer vertically, for like a 1h-4h, hoping that gravity will make gradient in PR thickness, than make UV. Unfortunatelly, I did not achieve the slope. I used SU 25 for this. Is there some other way to prepare oblique microchannel? The desired sizes are: length - approx. 4cm, initial heigth 200um, final heigth 20um. I want to make like this: http://img193.imageshack.us/img193/5440/46006411.jpg Also the ways to prepare slopes with angles 30-70 degrees are strongly wanted. Thanks in advance!