This is a typical example of my virtual domain configuration (Apache 1):ServerName my.server.name DocumentRoot /path/to/my/site/ Alias /html/ /path/to/static/files/ and minimal Quixote 1 script: #!/usr/bin/env python from scgi.quixote_handler import QuixoteHandler, main from mylib import MyPublisher from mysite import root class MyAppHandler(QuixoteHandler): publisher_class = MyPublisher root_namespace = root() prefix = "" if __name__ == '__main__': main(MyAppHandler) > I've tried: > - without script-name on scgiscript > - with script-name="/" I think you should use script-name="" -- KseniaSCGIServer 127.0.0.1 4005 SCGIHandler On SCGIHandler Off