Dear Colleagues,

I seeking suggestions on suitable methods/devices of gas/liquid separation
used in the feed streams of microfluidic devices.

I am having problems with gas bubbles entering into my microfluidic devices
that contain many channels.  The bubbles block the normal liquid flows in
some of the channels.  My liquid manifold, which feeds my microfluidic
devices, is a commercial one and it inherently generate gas bubbles in the
feed stream.  I am seeking a gas/liquid separation device to insert between
the liquid manifold and my microfluidic device so that I can remove the gas
bubbles from the feed stream.  I am using multiple types of fluids at
low-volume flow conditions and I need to avoid the intermixing among them.
Therefore, the volume of the gas/liquid separation device must be small,
preferably smaller than 0.1 milliliter.  In addition, the material of the
device needs to be organic solvent and acid resistant.

I would appreciate to hear any suggestions on the availability of such a
gas/liquid separation device or how such a device can be made.

Thanks you,


X. Chuan Zhou, Ph.D.
Xeotron Corporation
xczhou@xeotron.com